The SuperSpin Micro Column allows screening of chromatography media at a miniaturised scale . It works in standard micro centrifuge. No expensive liquid-handling equipment is needed. Packing volume can vary from 10 µl to 400 µl. It can be adopted for either batch mixing-binding study or packed bed binding study.

The SuperSpin Micro Column contains a centrifuge tube and a filter frit. The tube is made of polypropylene and the frit made of polyethylene. The frit has a pore size of 10 µm. The device is supplied in non-sterilised condition. If sanitisation is required, a suitable reagent should be used. The column can’t be autoclaved.

The working liquid volume is up to 600 µl. Provided a chromatography resin is packed in the device, the recommended resin volume is under 400 µl.

In comparison to the 96-well filter plate, it is a much flexible and cost-effective approach to process biological species of small volume. Samples from a few to dozens can be quickly processed in a standard bench top centrifuge.

SuperSpin Micro Column is particularly useful for the following applications:

• Processing of low to high quantity of samples
• Packing of small volume of chromatography resin
• Depletion of proteins
• Screening of chromatography resin
• Screening of purification parameter
• Purification process development