BioToolomics offers low cost but high performance empty disposable chromatography columns: a choice of 2.5 ml, 5 ml, 10 ml or other volumes.

Glass columns are too expensive that people can’t afford a large inventory. A user has to pack, unpack and repack the same column for different purification tasks. In particular, it could be very inconvenient if a laboratory needs to purify a good number of different molecules.

BioToolomics range of disposable chromatography columns has all the functionalities of small glass columns but possesses many other advantages: low cost, flexible, resin compressibility taken into account, disposable, easy to pack, tight packing of any type of chromatography media (>20 micrometer), identical design to the scale-up columns, robust, precise and reproducible packing, allowing moderate back pressure, easy to store, long life time.

After the chosen resin is packed in the column, the column can be readily stored and used for many times during the life time of the packed resin. Due to its low cost, a user can afford to assign individual columns for the purification of individual molecules.

The column body (i.e. the tube) is made of acrylic. It has the appearance similar to glass tube, i.e. clear and transparent.

The End Plug is made of polypropylene. In one end, it has the standard connection (10.32 UNF female thread) compatible to the common chromatography instruments (such as AKTA). In the other end, it has two layers of mesh (coarse and fine) giving excellent flow distribution. The void volume in each End Plug is minimal as the fluid is introduced through a narrow flow path (i.e. 1 mm hole). Two O-rings are used in the End Plug to seal and secure the column.

The packed resin volume is 0.95 ml /cm bed height.

The column material shows excellent chemical resistance to most of the commonly used reagents. The recommended operational pressure is up to 3 bar (42 psi).